A Research Laboratory of Neuroimmunology, Neurotrauma, and Behavior

Michael Weber, Ph.D.

(Co-advised by Dr. Michele Basso and Dr. John Seridan)

B.S. Psychology, Ohio State University  (2008)

Ph.D. Behavioral Neuroscience/Psychology, University of Colorado (2015)

​Thesis Title: "Stress sounds the alarmin; High Mobility Group Box 1 as a stress-induced neuroinflammatory priming signal" 

Current Position:Postdoctoral Researcher at Nationwide Children’s Hospital, Columbus, OH.

Starr Jiang (2017-Current)
B.S. Neuroscience, Honors

Dunni Adekunle-Adegbite (2018-Current)
B.S. Microbiology

John Velaquez (2017-Current)

B.A. Neuroscience and Behavior

University of Notre Dame (2017)

Damon DiSabato

(Co-advised by Dr. Ning Quan) 

​Neuroscience Graduate Program, NGP (2014-current)

​B.S. Neuroscience and Psychology, Honors (2014) Ohio State University

My research interests focus on IL-1 signaling and its effects on the various cells of the CNS, particularly in regard to stress and anxiety. I use a myriad of cell-type specific Cre recombinase mouse lines to restrict the expression of IL-1R1 to discrete cells in order to delineate their responses to a murine social defeat paradigm. 

Current Postdoctoral Scholars

Brant Jarrett, Ph.D.​

B.S. Psychology, M.S. Psychology, Bringham Young University

Ph.D. Neuroscience, The Ohio State University (2009 - 2013)

​Thesis Title: "Chemotherapy Induced Deficits in Cognition and Affective Behavior"

Postdoctoral Researcher with Dr. Godbout (2013 - 2014)
Current Position: 
Regional Director of Medical Affairs at Mallinckrodt Pharmaceuticals 


Eric Wohleb, Ph.D.

Neuroscience Graduate Program (2008 - 2013)

Thesis Title: "Stress-induced Monocyte Re-distribution and Microglia Activation Underlies Development and Recurrence of Anxiety"

Current Position: Assistant Professor of Neuroscience, University of Cincinnati

Christopher Henry, Ph.D.

Ohio State Biochemistry Program (2006 - 2011)

Thesis Title: "Role of Primed Microglia in the Aging Brain in Prolonged Sickness and Depressive Behavior Concomitant with Peripheral Immune Stimulation."

Current Position: Postdoctoral Researcher at Nationwide Children’s Hospital, Columbus, OH.

Angela Wynne Corona, Ph.D.

Neuroscience Graduate Program (2007 - 2011)

Thesis Title: "Regulation of Microglia in the Brain by Fractalkine signaling: Implications for inflammation-associated sickness and depression."

Current Position: Business Development Manager at BioMotiv, Cleveland, OH


Former Undergraduate Students

Megan Muccigrosso

B.S. Biological Science, Minor in Psychology, University of Missouri, Columbia (2011)

M.S. Biomedical Sciences, Neuroscience, The Ohio State University (2012-2015) 

Thesis Title: "Cognitive Deficits after Traumatic Brain Injury are Exaggerated by Microglia-Associated Reactivity to Immune Challenge"

Current Position: Marketing Coordinator at Chemline Inc., St. Louis, Missouri

Current Graduate Students

Jackie Fontana (2017-2018)
B.S. Biochemistry, Honors

Chelsea Bray (2015-2018)

B.S. Neuroscience, Clinical Psychology Minor

Current Position: Research Assistant in the Godbout Laboratory

Alan Gordillo​ (2016-Current)

B.S. Microbiology, Honors



Sabrina Lisboa (2015-2016)

​PhD, Pharmacology- Faculdade de Medicina de Ribeirão Preto - USP

Home University: University of Sao Paulo- Ribeirao Preto, SP, Brazil


Kyle Atcheson (2013-2015)

B.S. Biomedical Science, Honors

​Current Position: ​Medical Student at the University of Pittsburgh

Paige Trojanowski (2013-2016)

​B.S. Neuroscience, Honors

Thesis Title: "Sequential Activation of Microglia and Astrocyte Cytokine Expression Precedes Alterations in Immunoreactivity Following Systemic Immune Challenge"

Current Position: Clinical Psychology Graduate Student at George Mason University  

Joni Ford (2013-2016)

B.S. Neuroscience

Copyright © Godbout Laboratory. All rights reserved.

Former SUCCESS Students

Principal Investigator

Allison Dugan (2010 - 2013)

B.S. Biology, Honors

Thesis Title: "Regulation if the Central Nervous System Inflammation by Anti-inflammatory Cytokines in Activated Microglia and Impairments in Aging" 

Current Position: Graduate Student, University of Texas Health Sciences Center San Antonio TX 


Former Trainees

Diana Norden, Ph.D.

(Co-advised by Dr. Michele Basso and Dr. John Seridan)

B.S. Biochemistry & Chemistry, Campbell University (2010)

Ph.D. Biochemistry, Ohio State University (2011-2015)

​Thesis Title: “Astrocyte Mediated Regulation of Activated Microglia: Implications for Exaggerated Microglial Activation in Aged Mice Following Peripheral Inflammatory Challenge” 

Current Position: Postdoctoral Researcher at Drexel University, Philadelphia, PA 

Current Undergraduate Students

Julia Dziabis (2016-Current)

B.S. Neuroscience, Honors

Caleb Gaffney (2016-2018)

B.S. Zoology, Kent State University (2014)

Current Position: Laboratory Assistant at Nationwide Children's Hospital 

Julia Kumar (2016-Current)
B.S. Neuroscience, Honors

Former Research Staff

Christopher Burnsides (2013 - 2014)

B.S. Biological Sciences, The Ohio State University (2008)

Graduated from Ohio State with a B.S. in Biology, with an emphasis on human physiology, and recently began medical school at Ohio University as part of the class of 2018.

Elisa Navarro (Summer 2014 - Winter 2014)

Physiology and Pharmacology Program (2012-current) (Universidad Autónoma de Madrid, Spain)

B.S. Biochemistry, UCM, Spain

Home University: Universidad Complutense de Madrid, Spain

​​

Former Visiting Scholars

Emmanuel Villanueva (Summer 2014)

NIGMS MARC Undergraduate Student in Training

Home University:  University of California, Merced

Katie De La Rosa (Summer 2012)

OSUMC SUCCESS Program Summer Student

Home University:  Dartmouth College, Hanover, NH

Jung Park (Summer 2013)

OSUMC SUCCESS Program Summer Student
Home University:  Brandeis University, Boston, MA


Anthony Cleland (2008 - 2010)

B.S. Biology, Honors

Thesis Title:  "TGFbeta Increases CX3CR1 Expression and Attenuates Lipopolysaccharide (LPS) Induced Microglia Activation."
Current Position: ​Medical Student at Lake Erie College of Osteopathic Medicine

Daniel McKim

(Co-advised by Dr. John Sheridan)

Ph.D Neuroscience, Ohio State University (2012-2017)

B.A. Psychology and Biopsychology Honor(2011) 

The William Paterson University of New Jersey

My research is concerned with the role of peripherally derived brain macrophages in the development of brain and behavior changes following psychological stress. I am particularly interested in molecular communication pathways between perivascular brain macrophages and brain vascular endothelial cells. 

Daniel Eiferman, M.D. (2013-Current)

B.A. Molecular and Cellular Biology, Northwestern University (1999)

​Doctor of Medicine, University of Kentucky (2003)

​Surgical Residency, Rush University, (2009)

​Surgical Critical Care Fellowship, The Ohio State University (2010)

Dr. Eiferman serves as Chair of The Clinical Quality and Patient Safety Committee and Assistant Program Director in Surgical Critical Care here at The Ohio State University Wexner Medical Center. He is an expert in the clinical aspects of traumatic brain injury and a key collaborator of the Godbout lab.

Wenyuan (Ren) Yin

Medical Scientist Training Program, MSTP (2016-current)

Neuroscience Graduate Program, NGP (2016-current)

B.A. Biology (2016) Louisville University 

My research focuses on changes in blood-brain permeability following psychosocial stress. I am particularly interested in the peripheral immune cell contribution to BBB breakdown. I also investigate bidirectional communication between neurons and microglia that can alter neuroinflammation after stress.


Clinical Research Protégés

Chelsea Bray (2018-Current)

B.S. Neuroscience, Clinical Psychology Minor

The Ohio State University (2018)

Brooke Benner (2014-2016)

B.S. Biology, Minors in Chemistry and Exercise Science, University of Mount Union (2014)

Current Position: Graduate student at The Ohio State University Biomedical Sciences Graduate Program


Anzela Niraula, Ph.D

(Co-advised by Dr. John Sheridan)

Neuroscience Graduate Program, NGP (2013-current)

B.A. Neuroscience (2011) Bates College

​Thesis Title: "Blood-borne factors regulate monocyte function during psychosocial stress: a case of corticosterone and IL-6".
Current Position: 
Postdoctoral Researcher at Veterans Affairs Medical Center, Seattle, WA.


John Skendelas (2010 - 2013)

B.S. Microbiology, Honors

Thesis Title: ​​"Methylene Blue Reduced Brain Edema, Neuroinflammation, and Behavioral Deficits associated with a Moderate Traumatic Brain Injury."

Current Position: Medical Student at The Ohio State University

Caroline Sawicki

(Co-advised by Dr. John Sheridan)

​D.D.S/PhD Program (2012-current)

B.S. Pre-Dentistry (2013) University of Dayton 

My research focuses on elucidating the mechanisms underlying stress-induced immune cell trafficking to the brain that leads to the development of a reactive endothelium and changes in behavior. In particular, I’m looking at the crosstalk between neurons, microglia, and endothelial cells in facilitating brain-myeloid cell trafficking via chemokine signaling and vascular adhesion molecules. 

Jonathan Godbout, Ph.D.

Professor of Neuroscience 

B.S. Cell and Structural Biology (1996) University of Illinois-Urbana

Ph.D.  Biochemistry (2001) University of Illinois-Urbana. 

Postdoctoral Fellow (2001-2005) University of Illinois-Urbana

My Ph.D. training was in the laboratory of Gregory Freund, M.D.  I continued at the University of Illinois as a postdoctoral fellow with Rodney Johnson, Ph.D.  In 2005, I was hired as an Assistant Professor at The Ohio State University Wexner Medical Center. In 2012, I was tenured and promoted to the rank of Associate professor and in 2017 I was promoted to full professor. Currently, I am in the Department of Neuroscience, Institute for Behavioral Medicine Research, and Center for Brain and Spinal Cord Repair at the OSU Wexner Medical Center. My research interests are neuroimmunology, neurotrauma, and behavior.  

Aline Sayd Gaban (Fall 2016 - Winter 2016)

B.S. in Biological Sciences

M.A. Biochemistry

Ph.D Biomedical Research (Current)

Home University: Universidad Complutense de Madrid (UCM)


Current Research Staff

Harsha Pulluru (2018-Current)
B.S. Neuroscience

Ashley Fenn, Ph.D.

B.S. Zoology & B.S. Biochemistry, Colorado State University (2009)

Ph.D. Neuroscience, The Ohio State University (2009 - 2014)

Thesis Title: "Mechanisms and Consequences of Microglial Priming and Dysregulated M2a Responses with Age and Central Nervous System Injury​"

Current Position: Associate at McKinsey & Company

Jared Smith (Summer 2014)

OSUMC SUCCESS Program Summer Student

Home University:  University of Alabama, Birmingham

Vikram Sharma (2012 - 2014)

B.S. Neuroscience

Daniel Mo​​ussa (2013-2016)

B.S. Biomedical Science, Honors

Thesis Title: "Treatment of Traumatic Brain Injury Using Methylene Blue Infusion"

Current Position:  Medical Student at the Cleveland Clinic Lerner College of Medicine

Jacqueline Lieblein-Boff, Ph.D.

Ohio State Biochemistry Program (M.S. 2005 - 2007, 2010 - 2012)

Thesis Title: "An Early-life Infection with E.coli in BALB/c mice causes long lasting deficits in Behavior, Brain Development and Microglial Reactivity"

Current Postion: Senior Scientist, Abbott Nutrition, Columbus, OH

Jenna Patterson (2012-2015)

B.S. Biology, Honors

Thesis Title: "The Role of the Spleen in Re-Establishment of Macrophage Trafficking to the Brain and Anxiety in Stress-Sensitized Mice"

Current Position: Medical Student at The Ohio State University 


Olga Kokiko-Cochran, Ph.D. (2016-Current)

Research Assistant Professor, Department of Neurology
B.A. Mount Union College (2003)

M.A. East Carolina University (2005)

Ph.D Virginia Commonwealth University (2008)
Manager, Rodent Behavioral Core at the Lerner Research Institute (2008-2012
)

Post-Doctoral Fellow, Lerner Research Institute (2012-2016)

My research focuses on the interrelationship between traumatic brain injury (TBI), neuroinflammation, and the development of Alzheimer's Disease (AD) - like pathology in experimental models. There is a widespread neuroinflammatory response following TBI, which includes microglial reactivity and recruitment of peripheral monocytes. Accumulating evidence suggests that these cell populations maintain a unique inflammatory profile as they respond to TBI and facilitate AD-like pathology in a cell specific manner. Ongoing research will examine the neuromodulatory effects (specific to microglia and monocytes) of accumulating beta-amyloid and microtubule associated protein tau (MAPT) following TBI.

Zoe Tapp

Neuroscience Graduate Program, NGP (2018-current)

B.S. Neuroscience (2018) University of Pittsburgh 



Emma Hans (2018-Current)
B.S. Neuroscience, Studio Art Minor

Shane O’Neil
Neuroscience Graduate Program, NGP (2016-current)
B.S. Neuroscience & B.A. Chemistry (2016) University of Rochester

My research interests focus on the age-associated dysregulation between the immune system and the central nervous system.  I am particularly interested in the impaired signaling between microglia and astrocytes in the aged brain.  I am also studying the profile of repopulating microglia in the murine brain after CSF1R-mediated depletion in the context of age-associated microglial priming.

Andrew Perl (2018-Current)
B.S. Neuroscience

Ravitej Alturi (2016-Current)
B.S. Neuroscience, Heath Sciences Scholars

Kristina Witcher

Medical Scientist Training Program, MSTP (2013-current)

Neuroscience Graduate Program, NGP (2013-current)

B.A. Biochemistry and Neuroscience (2013) Oberlin College 

My research is focused on understanding how microglia respond to traumatic brain injury (TBI). I utilize a murine model of diffuse brain injury to delineate microglia structural and transcriptional changes after TBI. I am particularly interested in how neuronal injury promotes microglial and astrocytic activation and how microglia affect long-term behavioral and structural neuropathology following brain injury.